Histoire naturelle et facteurs de risque du cancer colorectal au cours des maladies inflammatoires intestinales
Natural history and risk factors for colorectal cancer in inflammatory bowel disease
Patients with a Crohn’s or ulcerative colitis are at increased risk to develop a colorectal cancer. This risk starts to increase 8–10 years after diagnosis and reaches around 8 % after 20 years and 18 % after 30 years. Main risk factors are extensive colitis, long duration of the disease, associated sclerosing cholangitis and family history of colorectal cancer. These cancers are sometimes difficult to diagnose, often multifocal and occurring on flat or even normal-appearing mucosa. Mortality however does not seem very different from colorectal cancer in the general population.
E. LOUIS, J. BELAICHE
cholangitis, colitis, colorectal cancer, inflammatory bowel disease (IBD)